| Date | Location | Result | |
| 11/14/21 | Riverdale, NY | Fairfield 3, Manhattan 1 (25-19,22-25,25-13,25-19) | Box score |
| 11/13/21 | Riverdale, NY | Quinnipiac 3, Manhattan 0 (25-18,25-21,25-21) | Box score |
| 11/07/21 | Jersey City, NJ | Saint Peter's 3, Manhattan 0 (25-8,25-22,25-19) | Box score |
| 11/06/21 | Lawrence Twnp., NY | Rider 3, Manhattan 0 (25-15,25-20,25-17) | Box score |
| 10/31/21 | Niagara Univ., NY | Niagara 3, Manhattan 0 (25-21,25-11,25-21) | Box score |
| 10/30/21 | Buffalo, NY | Canisius 3, Manhattan 1 (25-14,26-24,20-25,25-18) | Box score |
| 10/27/21 | Riverdale, NY | Manhattan 3, Saint Peter's 1 (26-24,26-24,22-25,25-18) | Box score |
| 10/24/21 | Poughkeepsie, NY | Marist 3, Manhattan 0 (25-20,25-18,27-25) | Box score |
| 10/23/21 | Loudonville, NY | Siena 3, Manhattan 1 (18-25,25-11,25-16,25-19) | Box score |
| 10/17/21 | Hamden, CT | Quinnipiac 3, Manhattan 0 (25-21,25-22,25-17) | Box score |
| 10/16/21 | Fairfield, CT | Fairfield 3, Manhattan 0 (26-24,25-13,25-16) | Box score |
| 10/09/21 | Riverdale, NY | Iona 3, Manhattan 1 (25-18,25-23,16-25,25-22) | Box score |
| 10/06/21 | Riverdale, NY | Rider 3, Manhattan 0 (25-22,25-12,25-22) | Box score |
| 10/03/21 | Riverdale, NY | Canisius 3, Manhattan 0 (25-22,25-18,25-17) | Box score |
| 10/02/21 | Riverdale, NY | Manhattan 3, Niagara 1 (14-25,27-25,25-18,25-15) | Box score |
| 09/26/21 | Loudonville, NY | Siena 3, Manhattan 0 (25-13,25-16,25-15) | Box score |
| 09/25/21 | Poughkeepsie, NY | Marist 3, Manhattan 0 (25-19,25-12,25-18) | Box score |
| 09/18/21 | New Rochelle, NY | Iona 3, Manhattan 0 (25-14,25-11,25-13) | Box score |
| 09/08/21 | Dover, DE | Delaware State 3, Manhattan 0 (25-17,25-20,25-13) | Box score |
| 08/28/21 | Hackensack, NJ | UMES 3, Manhattan 0 (25-18,25-20,25-22) | Box score |
| 08/28/21 | Hackensack, NJ | Robert Morris 3, Manhattan 0 (25-22,26-24,25-17) | Box score |
| 08/27/21 | Hackensack, NJ | Fairleigh Dickinson 3, Manhattan 0 (25-10,25-16,25-18) | Box score |